I am currently a postdoctoral researcher at School of Medicine, UCSD. I have done my doctoral work under the guidance of Prof. Dr. Thomas Lengauer (Computational Biology and Applied Algorithmics group) at Max Planck Institute for Informatics, Germany.

Research Interests

Interdisciplinary research area of computational biology and bioinformatics, Systems biology, Mathematical modelling in disease-associated pathways, Software development (mass spectrometry, metabolomics, proteolytic pathways, PathwayDB and CutDB database), Statistical analysis and method development, Computational methods for Biomarker discovery in disease research(Diabetes and Kidney diseases)

Academic Degrees

Ph.D.(Computer Science), Computational Biology and Applied Algorithmics Group, Max Planck Institute for Informatics, Germany (2002-2007, degree awarded 2008)
Advanced Diploma (Bioinformatics), Bioinformatics Centre, University of Pune, India (2000)
M.Sc. (Biotechnology), Department of Biotechnology, Guru Nanak Dev University, Amritsar, India (1998)
B.Sc. (Chemistry), St. Stephen's College, Delhi University, India (1996)

Publications

9. Ravanan P, Sano R, Talwar P, Kondaiah P, JC Reed(2009)
Cyano Enone of Methyl Boswellate(CEMB) induces apoptosis by activating intrinsic and extrinsic pathways in prostate cancer cells.
(manuscript in preparation)

8. Talwar P, Rao SR, Ravasi T, Sharma K(2009)
A computational approach for elucidation of casual pathways of pirfenidone in Diabetic Nephropathy.
Advances in Bioinformatics, 2009(submitted)

7. Rao SR, Talwar P, Ravasi T, Sharma K(2009)
Pirfenidone targets protein translation.
Expert Review of Endocrinology and Metabolism, 2009(submitted)

6. Igarashi Y, Heureux E, Doctor KS, Talwar P, Gramatikova S, Gramatikoff K, Zhang Y, Blinov M, Ibragimova SS, Boyd S, Ratnikov B, Cieplak P, Godzik A, Smith JW, Osterman AL and AM Eroshkin.(2009)
PMAP: Databases for analyzing proteolytic events and pathways.
Nucleic Acids Research, Database Issue, 2009

5. Talwar P, Schmidt M, Brill L, Wolf DA.(2008)
Computational analysis of the S. pombe proteome and transcriptome under oxidative stress condition.
North American Regional Pombe Meeting, Los angeles, June 6-8, 2008 (conference talk).

4. Velagapudi VR, Wittmann C, Lengauer T, Talwar P and E Heinzle.(2006)
Metabolic high- content screening of Saccharomyces cerevisiae reveals superior performance of single gene deletion strains.
Process Biochemistry, 41:2170-2179, 2006

3. Hahn A, Rahnenfuehrer J, Talwar P and T Lengauer.(2005)
Confirmation of human protein interaction data by human expression data.
BMC Bioinformatics, 6:112, 2005

2. Talwar P, Lengauer T, Wittmann C and E Heinzle.(2003)
A software tool for automated processing of ¹³C labeling data from mass spectrometric spectra
BioTechniques, 35:1214-1215, 2003

1.Talwar P, Das I, Appaiah MM, Loganathan U, See-Kiong Ng, Wong L and S Nair.(2002)
Challenges in Developing a Post-genome Knowledge Database.
Int. Society for Human Genomics, 27th Annual Meeting, Trivandrum, India, P21(71), 2002.

Refereed Conference Abstracts(Selected)

Rao SR, Talwar P, Ravasi T, Sharma K (2009).
Proteomics to Interactomics: A streamlined approach to identify high-yield hits.
In: HUPO 2009- VIII World Congress on Proteomics of Human Health: Environment and Disease, Toronto, Canada.

Rao SR, Talwar P, Ravasi T, Sharma K (2009).
Systems Biology approach to understanding mechanism of action of Pirfenidone.
In: American Society of Nephrology meeting, San Diego, USA.

Talwar P, Lengauer T, Wittmann C, Velagapudi V, Heinzle E (2006).
Development of Computational Methods for Analysis of Metabolic Profiling Data
Accepted In: International Conference on Systems Biology (ICSB 2006),Pacifico Yokohama , Japan.

Talwar P, Lengauer T, Rahnenfuehrer J, Heinzle E, Velagapudi V, Wittmann C (2005).
Towards computational analysis of metabolic profiling data for protein function prediction.
In: Yeast Systems Biology, 6th International Conference on Systems Biology (ICSB 2005), Boston, USA.

Talwar P, Lengauer T, Rahnenfuehrer J, Wittmann C, Velagapudi V, Heinzle E (2005)
Computational Methods for Protein Function Prediction using Metabolomics Data
In: International Workshop on Systems Biology 2005, Milan, Italy.

Talwar P, Lengauer T, Rahnenfuehrer J, Velagapudi V, Wittmann C, Heinzle E (2004)
Computational Methods For Metabolite Screening
In: 5th International Conference on Systems Biology (ICSB 2004), Heidelberg, Germany.

Talwar P, Lengauer T, Rahnenfuehrer J, Velagapudi V, Wittmann C, Heinzle E (2004)
Computational Methods For Metabolite Screening
In: 12th International Conference on Intelligent Systems for Molecular Biology + 3rd European Conference on Computational Biology (ISMB/ECCB 2004), Glasgow, UK.

Talwar P, Lengauer T, Wittmann C, Mangadu V, Heinzle E (2003)
Towards cellular function through metabolite screening
In: Metabolic Profiling: Pathways in Discovery, Abstract 7, Cambridge Healthtech Institute Conference.
(Abstract)

Professional Activities

Member of the Program Committee, Joint Automated Function Prediction(AFP)-Biosapiens SIG, Intelligent Systems for Molecular Biology(ISMB), Toronto, 2008.