Fall 2011 Schedule 

Date

Topic

Material

Textbook

9/22

Introduction: the revolution of genomics (23andMe intro)

Lecture 1

9/27

Genome wide association and linkage studies I

Lecture 2

pp. 21-32

9/29

Genome wide association and linkage studies II

Lecture 3

pp. 21-32

10/4

Genome size and complexity, Exons/Introns, Repeats

Lecture 4

pp. 203-221

10/6

Sanger sequencing reactions, automated sequencing, sequecing by hybridization, DNA synthesis

Lecture 5

pp. 203-221

10/11

MOVIE ("In the Family")

10/13

FIELD TRIP (Tour of the BioGEM Genomics Core on UCSD campus)

10/18

Next generation methods based on adapter sequencing, pyroseque

Lecture 6

pp. 32-52

10/20

Technologies for genotyping

Lecture 7

pp. 32-52

10/25

Ethical and legal issues of the personalized genomic era

Lecture 8

10/27

Expression technologies: Microarrays

Lecture 9

pp. 232-346, pp. 307-313

11/1

Expression technologies: cDNA/EST sequencing projects

Lecture 10

pp. 265-321

11/3

Protein sequencing by Edman degradation and mass spectroscopy

Lecture 11: testbook

pp. 265-321

11/8

Protein expression, phosphorylation, tagging

Lecture 12

11/10

MIDTERM

11/15

Comprehensive mutant libraries

Lecture 13

11/17

Protein interactions

Lecture 14

11/22

Grant Proposal Presentations

11/24

THANKSGIVING

11/29

Grant Proposal Presentations