Wk |
Num |
Date |
Theme |
Topics Covered |
Instructor |
Lecture |
Textbook Assignment |
Additional Reading |
0 |
1 |
9/27/2012 |
Introduction |
Introduction: The revolution of genomics |
Gabriel Pratt |
|
|
Initial sequencing and analysis of the human genome. Pages 1-16 |
1 |
2 |
9/27/2012 |
Genome structure |
Genome size and complexity, CoT curve analysis |
Trey Ideker |
Lecture 1 |
Chapter 1, esp. pp 27-52 |
|
|
3 |
10/4/2012 |
Genome Structure |
Exons/Introns, Repeats |
Trey Ideker |
Lecture 2 |
|
An integrated encyclopedia of DNA elements in the human genome |
2 |
4 |
10/9/2012 |
Gene association |
GWAS and linkage mapping I |
Trey Ideker |
Lecture 3 |
pp 27-32 |
|
|
5 |
10/11/2012 |
Field Trip |
Tour of the BioGEM Genomics Core on UCSD campus |
Gary Hardiman |
|
|
|
3 |
6 |
10/16/2012 |
Gene association |
GWAS and linkage mapping II |
Trey Ideker |
Lecture 4 |
|
|
|
7 |
10/18/2012 |
DNA sequencing |
Sanger sequencing reaction, automated sequencing, sequencing by hybridization, DNA synthesis |
Trey Ideker |
Lecture 5 |
pp203-221 |
Missing Heritability |
4 |
8 |
10/23/2012 |
DNA sequencing |
Next generation methods based on adapter sequencing, pyrosequencing, single molecule sequencing |
Trey Ideker |
Lecture 6 |
|
|
|
9 |
10/25/2012 |
DNA sequencing |
Next generation sequencing methods |
Trey Ideker |
Lecture 7 |
|
|
5 |
10 |
10/30/2012 |
DNA sequencing / mRNA expression |
Assembly / Expression Technologies: Microarrays |
Trey Ideker |
Lecture 8 |
pp. 265-304 |
|
|
11 |
11/1/2012 |
Genotyping / mRNA expression |
Expression Technologies: Microarrays |
Trey Ideker |
Lecture 9 |
|
|
6 |
12 |
11/6/2012 |
mRNA expression |
Microarrays |
Trey Ideker |
Lecture 10 |
|
|
|
13 |
11/8/2012 |
Proteomics |
Protein Expression |
Trey Ideker |
Lecture 11 |
|
|
7 |
14 |
11/13/2012 |
Proteomics |
Protein Tagging and Localization |
Trey Ideker |
Lecture 12 |
|
|
|
15 |
11/15/2012 |
MIDTERM |
ALL PREVIOUSLY COVERED MATERIAL |
Trey Ideker |
|
Textbook Assignment |
Additional Reading |
8 |
16 |
11/20/2012 |
Phenotyping |
Comprehensive Mutant Libraries |
Trey Ideker |
Lecture 13 |
|
|
|
17 |
11/22/2012 |
THANKSGIVING |
|
|
/td>
| |
|
|
17 |
11/27/2012 |
Phenotyping |
Comprehensive Mutant Libraries II |
Trey Ideker |
Lecture 13 |
|
|
9 |
18 |
11/29/2012 |
Interactions |
Protein Interactions |
Trey Ideker |
Lecture 15 |
|
pp. 381 - 404A |
10 |
19 |
12/4/2012 |
PRESENTATIONS |
|
Trey Ideker |
|
|
|
20 |
12/6/2012 |
PRESENTATIONS |
|
Trey Ideker |
|
|
|
|
12/14/2012 |
@11:59p |
PAPERS DUE |
|
|
|