| Wk | Num | Date | Theme | Topics Covered | Instructor | Lecture | Textbook Assignment | Additional Reading |
| 0 | 1 | 9/27/2012 | Introduction | Introduction: The revolution of genomics | Gabriel Pratt | Initial sequencing and analysis of the human genome. Pages 1-16 | ||
| 1 | 2 | 9/27/2012 | Genome structure | Genome size and complexity, CoT curve analysis | Trey Ideker | Lecture 1 | Chapter 1, esp. pp 27-52 | |
| 3 | 10/4/2012 | Genome Structure | Exons/Introns, Repeats | Trey Ideker | Lecture 2 | An integrated encyclopedia of DNA elements in the human genome | ||
| 2 | 4 | 10/9/2012 | Gene association | GWAS and linkage mapping I | Trey Ideker | Lecture 3 | pp 27-32 | |
| 5 | 10/11/2012 | Field Trip | Tour of the BioGEM Genomics Core on UCSD campus | Gary Hardiman | ||||
| 3 | 6 | 10/16/2012 | Gene association | GWAS and linkage mapping II | Trey Ideker | Lecture 4 | ||
| 7 | 10/18/2012 | DNA sequencing | Sanger sequencing reaction, automated sequencing, sequencing by hybridization, DNA synthesis | Trey Ideker | Lecture 5 | pp203-221 | Missing Heritability | |
| 4 | 8 | 10/23/2012 | DNA sequencing | Next generation methods based on adapter sequencing, pyrosequencing, single molecule sequencing | Trey Ideker | Lecture 6 | ||
| 9 | 10/25/2012 | DNA sequencing | Next generation sequencing methods | Trey Ideker | Lecture 7 | |||
| 5 | 10 | 10/30/2012 | DNA sequencing / mRNA expression | Assembly / Expression Technologies: Microarrays | Trey Ideker | Lecture 8 | pp. 265-304 | |
| 11 | 11/1/2012 | Genotyping / mRNA expression | Expression Technologies: Microarrays | Trey Ideker | Lecture 9 | |||
| 6 | 12 | 11/6/2012 | mRNA expression | Microarrays | Trey Ideker | Lecture 10 | ||
| 13 | 11/8/2012 | Proteomics | Protein Expression | Trey Ideker | Lecture 11 | |||
| 7 | 14 | 11/13/2012 | Proteomics | Protein Tagging and Localization | Trey Ideker | Lecture 12 | ||
| 15 | 11/15/2012 | MIDTERM | ALL PREVIOUSLY COVERED MATERIAL | Trey Ideker | Textbook Assignment | Additional Reading | ||
| 8 | 16 | 11/20/2012 | Phenotyping | Comprehensive Mutant Libraries | Trey Ideker | Lecture 13 | ||
| 17 | 11/22/2012 | THANKSGIVING | /td> | |||||
| 17 | 11/27/2012 | Phenotyping | Comprehensive Mutant Libraries II | Trey Ideker | Lecture 13 | |||
| 9 | 18 | 11/29/2012 | Interactions | Protein Interactions | Trey Ideker | Lecture 15 | pp. 381 - 404A | |
| 10 | 19 | 12/4/2012 | PRESENTATIONS | Trey Ideker | ||||
| 20 | 12/6/2012 | PRESENTATIONS | Trey Ideker | |||||
| 12/14/2012 | @11:59p | PAPERS DUE |