Ideker Lab - Trey G. Ideker

Trey Ideker is working to develop large-scale, computer-aided models of biological signaling and regulatory pathways. New types of models, experimental strategies, and statistical frameworks are needed for integrating the enormous amount of data on mRNA expression, protein expression, and protein interactions arising in the wake of the Human Genome Project. These tools will be crucial to the success of Systems Biology, i.e., understanding biological systems as more than merely the sum of their parts.

Ideker received bachelor's and master's degrees from MIT in Electrical Engineering and Computer Science, where he was elected to the HKN Engineering Honor Society and awarded the Northern Telecom/BNR prize for his work in digital circuit design. Encouraged by developments in the Human Genome Project, Ideker rapidly became interested in applying methods from computer science and engineering to the understanding of biological systems. Towards this goal, he obtained a Ph.D. in Molecular Biotechnology at the University of Washington and at the Institute for Systems Biology under Dr. Leroy Hood. He then moved to the Whitehead Institute for Biomedical Research, in Cambridge, Massachusetts, as the David Baltimore Fellow and Pfizer Fellow of Computational Biology. Dr. Ideker is currently a member of the Dept. of Bioengineering at U. C. San Diego, where he is Associate Professor. He serves on the advisory board of Genstruct and the BioCyc Project, has been a Bioinformatics Lecturer for ISTR, Inc., and holds several patents in the fields of microarray analysis and systems biology.