Our laboratory conducts bioinformatic and experimental research in the field of Network and Systems Biology. Click on the below links for more detailed information about each project.

BIOINFORMATICS. Our bioinformatics research is directed towards what we believe will be two critical approaches for biological network analysis:

* Methods for comparison of networks across different species, network types, biological conditions, or points in time.
* Methods for assembling individual molecular interactions into models of signaling and regulatory pathways.
* In addition, we are strong supporters of several community software projects, including the Cytoscape platform. We also are interested in Error Analysis and Modeling of DNA MIcroarrays.

GENOME-SCALE BIOLOGY. Experimentally, the lab is applying the above network modeling technologies to understand a variety of basic cell processes and diseases.

* Genome-scale approaches to understand how cells respond to DNA damage.
* Mapping protein networks in pathogenesis of disease (Malaria, Herpes, HIV and NeuroAIDS)
* Galactose Utilization as a Model System

Internal Lab Wiki (Lab project ideas and current research project descriptions)